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Without enough glycine, your bodys detox and antioxidant systems are weakened, leaving cells more vulnerable to oxidative stress, a key driver of aging and chronic disease

95% confidence interval, 11.2 to 9.5

This is needed for glutathione to function as an antioxidant and explains how riboflavin deficiency can depress its function [52]

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By integrating these mechanistic insights with emerging data on how disrupted lipid and glucose metabolism amplify immune dysregulation, the review underscores the interplay between metabolic and inflammatory pathways in exacerbating tissue injury across these organs

Autoimmun Rev 6:559565