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Patients were randomly assigned in a 1:1 ratio to receive once-weekly subcutaneous semaglutide at a dose of 2.4 mg or placebo

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One Year: Maximum weight loss benefits are usually achieved, provided patients adhere to a healthy lifestyle

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Most trials that produced the headline numbers enrolled patients who already had the disease being studied

Despite these promising findings, most gastroenterologists acknowledge that GLP-1 medications are not yet standard-of-care treatments for IBS, and patients should discuss potential benefits and risks with their healthcare providers before starting therapy