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Phase 2 results (48 weeks): 1mg dose: 8.7% average weight loss 4mg dose: 17.1% average weight loss 8mg dose: 22.8% average weight loss 12mg dose: 24.2% average weight loss Placebo: 2.1% average weight loss These numbers came from a 48-week study period, six months shorter than the 72-week SURMOUNT trials

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Certain medications may make it harder for your body to absorb B-12, including: Acid reflux and peptic ulcer disease medications, including: famotidine (Pepcid AC) lansoprazole (Prevacid) omeprazole (Prilosec) Metformin (Glucophage, Glumetza), a common type 2 diabetes treatment chloramphenicol, an antibiotic Very low levels of vitamin B-12 can result in serious complications, including anemia

That kind of opprotunity right now is very scarce, but options and accessibility may increase or diminish in the months ahead