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We also aimed to determine if there is sufficient evidence to exclude this association by means of trial sequential analysis (TSA)

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When conservative measures are insufficient, clinicians may recommend specific over-the-counter remedies or short courses of prescription antiemetics, always weighing safety, interactions, and patient comorbidities

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In addition, we used this matching approach to balance the covariates between the groups effectively

Metformin, an antidiabetic drug, represses hepatic glucose production by inhibiting mitochondrial glycerophosphate dehydrogenase and altering hepatic redox status