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METHODS We conducted an active-comparator-controlled, double-blind, noninferiority trial in which patients with type 2 diabetes and atherosclerotic cardiovascular disease were randomly assigned in a 1:1 ratio to receive a weekly subcutaneous injection of tirzepatide (up to 15 mg) or dulaglutide (1.5 mg), an agent that has been shown to reduce the incidence of cardiovascular events
Its site also displays a LegitScript verification link, though this article couldn't independently confirm current certification status through LegitScript's own public lookup tool
Notably, NR4a1s translocation from the nucleus to mitochondria underscores its vital role in mitochondrial function regulation 66 , suggesting that targeting NR4a1 to improve metabolism may offer significant therapeutic benefits
Gastroparesis is a gastrointestinal disorder characterized by delayed emptying of the stomach contents into the small intestine, leading to a range of uncomfortable symptoms