References Marzook, A., Tomas, A., & Jones, B
The (AEEEK) 3 rigid linker keeps domains apart and ensures a rigid separation of the individual domains of the fusion proteins
Lancet Oncol 22 (8): 1126-1138, 2021
"While there are many drugs used to treat type 2 diabetes (sulfonylureas, DPP-4 inhibitors, SGLT-2 inhibitors, TZDs, GLP-1 agonists, etc.), these results may make Jardiance or other SGLT-2 inhibitors the standard second-line therapy (after metformin) used to treat type 2 diabetes (or potentially first-line therapy if the magnitude is really meaningful we wont know anything about that for a month, when the specifics on the results are disclosed)
Expert Opin Drug MetabToxicol
For micro-dosing, the concentration you create determines measurement precision