tirzepatide exhaustion Does Fatigue Go Away? Timeline and Management Does Tirzepatide Make You Tired?

Main Effects and Benefits

Most widely known as Ozempic and Wegovy, Semaglutide is a GLP-1 agonist, meaning it mimics the peptide hormone GLP-1

Russell-Jones et al

By activating the receptors for both GLP-1 and GIP, tirzepatide helps your body in several ways: Enhances insulin secretion in response to meals Reduces glucose production by the liver Slows stomach emptying, leading to increased feelings of fullness These combined effects help regulate blood sugar and curb appetite, making it easier for patients to reduce food intake and achieve sustainable weight loss

doi: 10.1016/j.biopsych.2015.11.024

This study highlights that people with T2D who have either established or are at high risk for CV disease might benefit from semaglutide use, regardless of the degree of weight loss they achieve