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2.13 Mass spectrometry 2.13.1 Hydrogen-deuterium exchange mass spectrometry (HDX-MS) Time-resolved spontaneous hydrogen-deuterium exchange (HDX) of covalently bonded hydrogens of a protein with deuterium in solution provides information about protein conformation, flexibility, and solvent accessibility (Englander et al., 2016)

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JAMA Internal Medicine, 184 (7), 854

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Reads were subjected to trimming using Trim galore 0.6.4 115 , and then aligned to the genome using Hisat2 2.2.0 116,117

More important than concentration is the formulation's pH stability (GHK-Cu is stable between pH 5.0 and 6.5) and the carrier's ability to deliver the peptide past the skin barrier