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Some of the GLP-1 based medications available on the U.S

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5355 In the established model of insulin secretion, islet beta-cells glucokinase firstly senses that the serum concentration of glucose is 5mM or greater, which triggers glycolysis leading to ATP production, glucose oxidation and ultimately insulin secretion

DURATION-1: exenatide once weekly produces sustained glycemic control and weight loss over 52 weeks

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