TGF-, which plays a vital role in the development of PF, can stimulate airway smooth muscle hyperresponsiveness, goblet cell hyperplasia, and increased mucin secretion through Smad signaling (Ouyang et al., 2010
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Addressing obesity is crucial because its linked to severe health conditions like type 2 diabetes and heart disease
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In one late 1990s study, (6) a clinical trial was conducted on eight male test subjects with a concentration escalation design