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Int J Food Sci Technol

A large trial reported in 1994 (pdf) that daily megadoses of the antioxidant beta-carotene increased the risk of lung cancer in male smokers by 18 percent and a 1996 trial was stopped early after researchers discovered that high-dose beta-carotene and retinol, another form of vitamin A, increased lung cancer risk by 28 percent in smokers and workers exposed to asbestos

B.WangQ.LongY.ChengZ.ChenS.ZhengH.et al

In addition, the N-terminal thioredoxin-like domain of GST, known as the G-site, is responsible for GSH binding 22

Taken together, these studies indicate that inducing ferroptosis in HSCs may represent a viable strategy for treating and/or preventing liver fibrosis

Glutathione helps protect them