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DISCUSSION In the base-case analysis assuming two retreatments with semaglutide 2.4 mg, the ICER was 5 300 580/QALY in the non-T2D population and 7 077 984/QALY in the T2D population

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CBT helps individuals: Identify negative thought patterns Recognize cognitive distortions Understand the connection between thoughts, feelings, and behaviors Challenge unhelpful beliefs Develop healthier coping strategies Reduce anxiety-related avoidance Many people begin noticing improvements within a few weeks of consistent treatment