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Power calculations suggest that previous studies would have had limited power to detect an effect size similar to that identified in our study (Supplementary Table 23), and also differed in terms of drug type, disease cohort and analytical choices

Clinical grade BSO was provided via an NCI Rapid Access to Intervention Discovery (RAID) grant to CPR

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usually, the number of elderly patients is very limited, not to mention the follow-up duration, usually up to 5 years (in this analysis, the follow-up ranged from 5 to 24 years) [365]

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LC-MS identity confirmed (mass 402 Da)