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Glutamate is converted to GSH via a two-step enzymatic process requiring ATP (glutamate-cysteine ligase and GSH synthase) and metabolized by the enzyme glutamate decarboxylase (GAD) to GABA, the main inhibitory neurotransmitter (21)

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205,206 Animal models have also shown that zinc solutions protect against vaginal or rectal HSV-2 infections and reduce rates of viral shedding