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MicroRNA-194: a novel regulator of glucagon-like peptide-1 synthesis in intestinal L cells

"Enhanced weight loss outcomes with GLP-1 analogues and bupropion/naltrexone combination"

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A change in diabetes drug prescribing led to clinical trials of intranasal insulin administration, followed by insulin sensitizers, including metformin and peroxisome proliferator-activated receptor agonists, followed by incretin mimetics targeting primarily GLP-1R (GLP-1RAs) [106]

This is partly a nausea-related aversion effect