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Therefore, the reduced inflammatory cytokines seem to cause a global improvement in functioning and pain reduction in fibromyalgia patients (Table 1)

10.1126/science.aau2818 168 PanY.GanM.WuS.HeY.FengJ.JingY.et al (2024)

It was first discovered in human plasma in the 1970s and is found throughout the body, including in saliva and urine

When analyzed specifically by gene, 12/13 (96%) with MEK1 or MEK2 mutations reported keratosis pilaris, compared with 77% (36/47) in the participants with BRAF mutations

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While there was also an initial drop in Sutterella, this result was no longer significant after adjusting for age, body mass index (BMI), and gender