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2 and 3 of the ESM)

But they're not the only treatments of their kind

Between enrollment and delivery, maternal GSH concentrations tended to increase with NAC treatment (median: 47 mol/L), and to decrease under placebo (median: 8 mol/L, P 0.08) (Table 2B)

Because the specialty hospital sees a large percentage of NAION patients in the region, this could limit the generalizability of the findings