We're really trying to change societal narrative about this topic without it being polarizing
Sergey Terushkin, MD, FACS Board-Certified Surgeon
Constipation: common but manageable Constipation is frequently reported with GLP-1 therapy and may worsen with: Low fibre intake Reduced food intake Inadequate hydration A sedentary lifestyle Helpful measures may include: Adequate water intake Fibre-rich fruits and vegetables Walking or light physical activity Isabgol or fibre supplementation if medically appropriate To reduce nausea, many patients find relief by switching to lighter regional Indian meals and smaller portions during the first few weeks
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Combination with finerenone for cardiorenal protection Recently, in FIDELIO-DKD [52], FIGARO-DKD [53] and their pooled meta-analysis FIDELITY [11], finerenone has also been shown to reduce cardiovascular and renal events in CKD patients with diabetes
ASA/AGA/ASMBS/SAGES multi-society statement (Oct 2024)