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Tirzepatide's dual-action mechanism produces greater results than semaglutide alone with clinical trial data showing an average of 22.5% body weight loss

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The urine flows through the ureters and is stored in an internal pouch created from part of your bowel or in your bladder

Participants were also advised to follow a reduced-calorie diet and increased physical activity , so the results reflect medication plus lifestyle changes, not semaglutide alone