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Per unit mass, the myocardium consumes most of the KB (88, 89)

Mechanistically, studies indicate that the transition from hyperoxia back to normoxia paradoxically suppresses FAO while promoting ceramide synthesis, both pathways converging to promote apoptosis

doi: 10.1111/j.1360-0443.2012.04054.x 11 McPheetersMOConnorEARileySKennedyS