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Strongest human evidence (topical) The Leyden 2002 photoaging trial in 71 women applied a GHK-Cu facial cream for 12 weeks and reported measurable improvements in skin density, thickness, fine lines, and laxity

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Tooth loss and subsequent disability and mortality in old age

Theracurmin, a colloidal nanoparticle-based curcumin

Here are some of the most popular benefits: Reduces fine lines and wrinkles Improves skin tone and texture Fades sun damage and age spots Minimizes the appearance of acne scars Helps clear active acne and clogged pores Brightens dull or uneven skin Safe and effective for all skin types and ethnicities Most people see visible improvement after just one treatment, although a series of peels may be recommended for deeper concerns like acne scarring or more advanced pigmentation

doi: 10.1111/j.1742-4658.2008.06542.x 39 MargolisS