J Gastroenterol Hepatol (2015) 30:10916
Semaglutide Bin son v Hiu nh Dc s Xun Ho Danh php Tn chung quc t Tn danh php theo IUPAC 18-[[(1 R )-4-[2-[2-[2-[2-[2-[2-[[(5 S )-5-[[(2 S )-2-[[( 2 S )-2-[[(2 S )-5-amino-2-[[2-[[(2 S )-2-[[(2 S )-2-[[(2 S )-2- [[(2 S )-2-[[(2 S ) -2-[[(2 S )-2-[[(2 S )-2-[[(2 S )-2-[[(2 S ,3 R )-2-[[(2 S )-2-[[(2 S ,3 R )-2-[[2-[[(2 S )-2-[[2-[[(2 S )-2-amino-3-(1 H-imidazol-5-yl)propanoyl]amino]-2-metylpropanoyl]amino]-4-cacboxybutanoyl]amino]axetyl]amino]-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino] -3-hydroxypropanoyl]amino]-3-carboxypropanoyl]amino]-3-metylbutanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4- metylpentanoyl]amino]-4-cacboxybutanoyl]amino]axetyl]amino]-5-oxopentanoyl]amino]propanoyl]amino]propanoyl]amino]-6-[[(2 S )-1-[[( 2 S ) -1 -[[(2 S ,3 S )-1-[[(2 S )-1-[[(2 S )-1-[[(2 S )-1-[[(2 S )-1-[ [(2 S )-5-carbamimidamido-1-[[2-[[(2 S)-5-carbamimidamido-1-(cacboxymetylamino)-1-oxopentan-2-yl]amino]-2-oxoetyl]amino]-1-oxopentan-2-yl]amino]-3-metyl-1-oxobutan-2 -yl]amino]-4-metyl-1-oxopentan-2-yl]amino]-3-(1 H -indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2 -yl]amino]-3-metyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino] Axit -6-oxohexyl]amino]-2-oxoethoxy]etoxy]etylamino]-2-oxoethoxy]etoxy]etylamino]-1-carboxy-4-oxobutyl]amino]-18-oxooctadecanoic Nhm thuc Thuc h ng huyt Incretin Cht ch vn peptide-1 ging glucagon Cht ch vn GLP-1 M ATC A Thuc trn s chuyn ha A10 Thuc iu tr cho bnh i tho ng A10B Thuc gim Glucose huyt A10BJ Cht tng t glucagon-like peptide-1 (GLP-1) A10BJ06 Semaglutide M UNII 53AXN4NNHX M CAS 910463-68-2 Cu trc phn t Cng thc phn t C 187 H 291 N 45 O 59 Phn t lng 4113.641 g/mol Cu trc phn t Semaglutide l mt polypeptide cha mt chui tuyn tnh gm 31 axit amin c ni vi nhau bng cc lin kt peptide
Semaglutide (oral/injection) (en espaol) Generic name: semaglutide (oral/injection) Brand names: Ozempic, Rybelsus, Wegovy (0.25 mg dose), Wegovy (0.5 mg dose), Wegovy (1 mg dose), Wegovy (1.7 mg dose), Wegovy (2.4 mg dose) Drug class: GLP-1 Drugs Qu es semaglutide
From a regulatory point of view, Ozempic has been authorised in the European Union by the European Medicines Agency (EMA) since 2018, and in Spain by the AEMPS
and with which third parties, if any, health information is shared beyond the clinical care team
Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway
