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It can have a significant impact on the digestive system since it delays gastric emptying, which may affect the absorption of other oral medications

2016;12(2):e1005878

That part isnt always clear

Melatonin helps your body get ready to fall asleep

Cochrane Database Syst Rev (1999) 2011(4):2167

We order vitamin B12 and folate testing when a person with Down syndrome we are evaluating has symptoms described above, has a lab abnormality for which follow up testing of vitamin B12 and/or folate is indicated, or the person has a condition in which deficiency is common (e.g., celiac disease)