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Microdosing is an off-label use of GLP-1 medications and is not FDA-approved for the indications discussed herein

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While no significant changes were observed in free testosterone or SHBG levels, treatment with GLP-1 RAs was associated with a significant rise in bioavailable testosterone and a notable reduction in HbA1c, indicating potential dual metabolic and endocrine benefits

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A Study of Retatrutide (LY3437943) in Adults With Obesity (TRIUMPH-1)