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GSH and similar antioxidant enzymes are lower in the blood of patients with MDD compared to controls, suggesting that there is an effect of GSH in the pathology of MDD (Maes et al

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Plasma concentrations decline significantly with age from approximately 200 ng/mL at age 20 to ~80 ng/mL by age 60 making it a compelling target for age-related tissue maintenance and periodontal health

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Further, acute trimetazidine injection (5 or 10 mg/kg) significantly decreased ROS in cardiomyocytes in rats with myocardial infarction [173]