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On the other hand, nitrogen stress cannot always be extinguished by behavioral modification, as in the case of AD and other neurodegenerative syndromes

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This prevents the "flushing" effect that often happens with high-dose vitamin C tablets, where the excess is simply excreted in the urine because the body cannot process it fast enough

Comparison with CRH-induced corticotropin and cortisol secretion Biologial Psychiatry, 1988 Jun, Volume 24 (Issue 2), Pages 162-72