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Mediation analysis indicated that the association between MASLD and T2D was partially mediated by elevated BCAAs, with a mediation proportion of 19.6% (74), suggesting that elevated circulating BCAAsreflecting impaired catabolic disposal at the non-cirrhotic disease stagerepresent a critical metabolic link between MASLD and T2D

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However, if the weight loss unmasks underlying androgenetic alopecia (pattern hair loss), that component is progressive and requires separate treatment

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The DAVID database was used to perform GO enrichment and KEGG pathway analyses based on the selected core target genes, and the results were presented in Figs

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Additionally, significant weight loss can influence metabolic parameters in individuals with obesity-related conditions

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Cagrilintide binds to amylin and calcitonin receptors , thereby enhancing feelings of fullness, reducing food intake, and supporting body weight reduction

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