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The final confirmation of the diagnosis is made by post-mortem neuropathological analysis

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18-5 ) again are associated with G6PD deficiency, and overwhelming evidence indicates that they have become polymorphic as a result of malaria selection (discussed later in this chapter)

Genetic contributors Recent advancements in genomewide association studies (GWAS) have shed light on potential genetic pathways implicated in PHG, offering a better understanding of the underlying mechanisms