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Most people start with a loading phase, typically one injection per week for 4 to 6 weeks

doi: 10.1007/s11892-020-1284-5 172 GrugniGCrinABedogniGCappaMSartorioACorriasAet al

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Koibuchi et al

Headaches : Mild headaches are possible, especially in the first few weeks

And, it was recently FDA approved to reduce the risk of cardiovascular death, heart attack, and stroke in adults with cardiovascular disease and obesity or overweight