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In particular, the GH 24 h secretion is decreased, along with the reduction of insulin-like growth factor I (IGF-I) production and a lower response of GH to stimulation tests [44]

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doi: 10.1007/s43440-020-00082-6

The investigators did not control for known prognostic factors or effect modifiers (e.g., environmental or socioeconomic factors) within the analyses, and establishing a causal link between the treatment and the growth outcomes is not possible