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According to Novo Nordisk 's published phase III clinical trial data submitted to the FDA, participants assigned to oral Wegovy experienced average weight reduction outcomes in the low-to-mid-teens percentage range over the study period, while placebo groups demonstrated substantially lower changes

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The most common side effects are gastrointestinal (nausea, diarrhoea, constipation), typically mild to moderate and improving over time

1 The proportion of participants reaching each weight-loss threshold: Among participants who completed the full course at the maintenance dose, average weight loss reached 16.6%