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S., & DeLany, J

Biomarkers and algorithms for the diagnosis of vitamin B12 deficiency

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54 More importantly, a massive NADH production by this pathway is known to perturb redox imbalance between NADH and NAD + , and consumption of NADPH can impair the function of glutathione reductase, leading to accumulation of oxidized form of glutathione and further accentuation of redox imbalance