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Survodutide is another dual agonist in development, targeting GLP-1 and glucagon receptors

Lab Monitoring : For patients with liver disease, regular monitoring of liver enzymes (ALT, AST) and other markers helps track progress and adjust treatment

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The most notable additional concern is a greater increase in resting heart rate, likely related to glucagon receptor activation

Pre-treatment considerations should include: Disease activity assessment : GLP-1 agonists should ideally be initiated when Crohn's disease is in remission or well-controlled, as distinguishing medication side effects from disease flare becomes challenging during active inflammation Nutritional status evaluation : Patients with Crohn's disease may already have compromised nutritional status

This makes it an appealing option for individuals seeking performance support and faster bounce-back after training or competition