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In women, higher BMI (body mass index) is linked with: Irregular or absent periods and anovulation

Average weight loss is about 5-8% of body weight

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This table compares the active ingredients, FDA-approved usage, and typical weight loss or A1C reduction of some of the most well-known GLP-1s: Semaglutide vs tirzepatide Semaglutide is the active ingredient found in the injectable medications Ozempic and Wegovy (and the oral medication Rybelsus)