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In a recent evaluation of a representative GLP-1 receptor agonist, we compared optimized linear SPPS with fragment-based routes under realistic manufacturing assumptions

Interestingly, while this study discovered that CHAC1/BOTCH-mediated regulation of GSH levels controls development, other studies suggest its developmental role is primarily based on the inhibition of NOTCH1 signaling (Yadav et al., 2019)

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Ristoff, E., Mayatepek, E