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Thus, decreased T cell activation owing to 710 day fasting suggests a transient immunosuppression, thereby suppressing RA (74)

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This process is characterized by the inhibition of System Xc, suppression of GPX4, and activation of key enzymes such as ACSL4 and LPCAT3 [9, 10], key regulatory mechanisms encompass redox homeostasis, iron metabolism, mitochondrial function, and amino acid/lipid/sugar metabolism [11]

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doi: 10.1177/2041731414566529

Third, our study was a multicenter prospective trial, which enhances the quality of evidence obtained compared to previous studies