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Nutrients, 10 (3)

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The etiology and pathophysiology remain incompletely understood

This has direct implications for research design: studies examining physiological GH patterns favor secretagogues, while studies requiring controlled supraphysiological GH levels use exogenous HGH

In keeping with this concept, exposure of human spermatozoa to ROS generated by xanthine oxidase disrupts the functional competence of spermatozoa at levels that have little impact on somatic cells and, importantly, this effect can be reversed by the addition of catalase [21, 22]