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Given the above correlation, we predict that a possible thyroid-gut-microbiome-brain axis is involved in the pathogenesis of mental disorders, thereby increasing the risk of depression

GGT levels in the blood are influenced by factors like age, gender, hormones, diet, medications, and substances that can harm the liver, as well as the kidneys, pancreas, and bile ducts where GGT is also found41

Like other enzymes that transfer two-carbon groups, transketolase requires thiamine pyrophosphate (TPP) as a co-factor in the transfer reaction

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Injections bypass the digestive system, allowing direct absorption into the bloodstream

This mechanism contributes to significant weight loss observed in clinical trials