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Patients using these medications have shown significant weight loss, often ranging from 10% to 15% or more of their initial body weight, when combined with lifestyle interventions [1] [10]

Pharmacologically, GLP-1RAs enhance insulin secretion, slow gastric emptying, suppress apoptotic cell death, and increase proliferation of pancreatic -cells [15]

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Not only does it help to cleanse the body, but it also helps maintain proper muscle strength and high levels of fitness

It has therefore been a major interest to develop profiles for personalized medicine or treatment strategies including biomarkers for risk stratifications, which could end in a scenario where treatments are targeted to the patients that have the highest likelihood of responding

other genotypes, P = .0001)