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10.3390/ijms23094605 92 CrileG

[DOI] [PMC free article] [PubMed] [Google Scholar] 40.Huang L., Xiao W., Wang Y., Li J., Gong J., Tu E., Long L., Xiao B., Yan X., Wan L

GHK-Cu is used in in vitro studies on fibroblast cultures (collagen, fibronectin synthesis), in tissue models (ECM remodeling) and in in vivo studies on animal models (angiogenesis and connective tissue remodeling processes)

A study has found that NRF2 is responsible for maintaining the self-renewal function of glioma stem cells (GSCs), supported by the evidence that NRF2 deficiency attenuated the tumorigenicity of GSCs in the xenograft model [129]

299 In addition, EZH2 represses AMBRA1 and LC3B , further reducing autophagic flux