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First, we restricted eligibility to primary studies published in peer-reviewed journals indexed in major international databases (e.g., Web of Science Core Collection and/or Scopus) and ranked within the top three quartiles (Q1Q3) of their subject category according to the most recent Journal Citation Reports (Clarivate Analytics, Philadelphia, PA, USA) or Scimago Journal Rank (Scimago Lab, Madrid, Spain) at the time of the search

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Furthermore, the newly available oral semaglutidethe first oral formulation of GLP-1 RA for the treatment of T2D [98]has shown efficacy, safety and tolerability in a number of studies [35, 44,45,46,47,48,49,50,51]

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The G6PD is fundamental for the cell's defense against the toxicity of reactive oxygen species (ROSs) (Figure 1)

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