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To date, it remains unclear how incretin-based therapies affect the mesolimbic circuitry to alter human eating behaviors

When absorption improves, the downstream results follow: steadier energy, fewer cravings, and better hunger control after meals

These effects are often more noticeable when starting treatment or increasing dosage, and may improve as the body adjusts

Na + -dependent transporters: the backbone of astroglial homeostatic function

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This is why tirzepatide outperforms semaglutide in most clinical studies