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The outer BRB is formed by the close contact between RPE cells and choroidal capillaries and is one of the factors that prevent abnormal components in the choroid from entering the retina (43)

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, 2019 ,doi: 10.1007/s10157-019-01727-4

Individuals at higher risk include older adults with reduced stomach acid production, people with gastrointestinal conditions affecting absorption, strict vegans, and those taking medications like metformin or proton pump inhibitors

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