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Bruising occurs when small blood vessels are disrupted, while repeatedly injecting in the same area can lead to thickened fatty tissue forming lumps

In a recent study, administration of exendin-4, a long-acting GLP-1RA, stimulated -cell proliferation in juvenile human islets by inducing gene expressions of calcineurin/nuclear factor of activated T cells (NFAT) signaling, a proliferating factor such as NFATC1, and a cell cycle regulator such as cyclin A1 [57]

Patients will receive detailed counseling about risks, benefits, and unknowns when it becomes available

Never inject in the same spot twice in a row

Healthcare facilities may have institution-specific protocols that reflect local expertise and patient populations

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