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Step 2: Consider Zepbound if Seeking Weight Loss If you want tirzepatide for weight loss and dont have a diabetes diagnosis, Zepbound may be easier to get covered by insurance (since its FDA-approved for that purpose) and offers better self-pay pricing through LillyDirect ($349 to $499 versus $1,000+ for Mounjaro)

- - - A new Oxford meta-analysis (P04.009, EASO 2025) confirms what many clinicians have observed: stopping GLP-1 receptor agonists often leads to rapid and near-complete weight regain within 12 years

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Furthermore, this medication reduced the risk of psychotic disorders, including suicidal ideation, bulimia, and schizophrenia

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