On March 5, Novo Nordisk released the top-line results from this pivotal kidney outcomes trial: Use of semaglutide in patients with diabetic kidney disease reduced the primary outcomea composite of kidney failure, 50% decline in estimated glomerular filtration rate (eGFR), and cardiovascular (CV) or kidney deathby an impressive 24% (Figure 1)
It promotes lipid mobilization from adipose tissue, enhances hepatic glucose modulation, and increases energy expenditure in ways that the GLP-1/GIP combination alone does not fully achieve
[1] [5] While rash is not among the most commonly reported side effects of Rybelsus, the Summary of Product Characteristics (SmPC) does note that hypersensitivity reactions can occur, which may include rash or urticaria (hives)
Fact: Hiccups are a mechanical response to changes in your digestive speed and stomach pressure, not a sign of toxicity
Antioxidant supplementation in sepsis and systemic inflammatory response syndrome
Many patients also report reduced appetite for foods they previously enjoyed, which is the intended therapeutic effect but can feel jarring