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10.1038/nature26138 20 GhoshM.GuptaP

"We don't know enough because we don't," he said

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It is administered as a once-weekly subcutaneous injection and represents a novel class of medication known as a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist

Its effects on blood sugar management include: Enhanced glucose-dependent insulin secretion Suppression of glucagon release Reduced hepatic glucose output Improved peripheral insulin sensitivity In most patients, semaglutide's glucose-lowering effects more than compensate for any minor glucose-raising effect from CJC-1295

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