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The homogenates were centrifuged at 20,400 g for 20 min at 4 C, and the resulting supernatants were appropriately diluted and used in the assays, which were conducted according to the manufacturers instructions

Other systemic effects (rare): Adults typically clear small amounts of benzyl alcohol without issue

Two studies were conducted to assess the effects of renal or hepatic impairment on pharmacokinetics, safety and tolerability following single doses of cagrilintide

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The breadth of documented effects comes from the peptides role as a gene expression regulator