To finish up the side effects, the discontinuation rate excluding the weight loss stoppages appears at least a bit more reasonable as in most obesity trials the stop rate is usually 5-8% which only leaves the 12mg as an outlier still, but like I said earlier, we need side effects over time and just more data in general to see whats going on with that dose
Your report will show: Insurance-covered options when available
Dose increases typically occur every 4 weeks based on your tolerance and weight-loss response
Slide from Katherine Tuttles presentation, during FLOW session, 61st European Renal Association Congress Conclusion The FLOW trial showed that semaglutide significantly decreased the risk of progression of kidney disease in T2DM, without significant increases in serious adverse events
obese ) Extreme overweight
The math is simple: you're adding roughly 0.5mg every two weeks, pausing at each level until the side effect picture is clear