nadph glutathione reductase Schematic representation of the role of the enzyme It favors its accumulation in Cell signaling nadph glutathione Potential Role of

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Roberts GW, Gentleman SM, Lynch A, Murray L, Landon M, Graham DI

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Although several human clinical trials have investigated the potential of oral NAC to replenish GSH in chronic depletions (e.g., in HIV patients), all have failed to give sufficient benefits to gain regulatory approval, even at high doses (up to 2 g/day) [103]

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